Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TYMP | P19971 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.40 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23778463 | 0.88 | TSHR (0.44) | TSHRTYMPPTPN1SLC6A1SLC6A11 | |
| SCHEMBL15512670 | 0.85 | TSHR (0.44) | TSHRPTPN1CA12CA9CA1 | |
| SCHEMBL4287805 | 0.83 | CYP3A4 (0.41) | TSHRTYMPPTPN1SLC6A1SLC6A11 | |
| SCHEMBL7025660 | 0.82 | TSHR (0.51) | TSHRPTPN1CA12CA9CA1 | |
| SCHEMBL18343982 | 0.81 | TSHR (0.50) | TSHRCYP2D6ALDH1A1KMT2A | |
| SCHEMBL22033902 | 0.81 | TSHR (0.39) | TSHRTYMPCA12CA9CA1 | |
| SCHEMBL9393500 | 0.81 | TSHR (0.50) | TSHRCYP2D6ALDH1A1KMT2A | |
| SCHEMBL22033884 | 0.81 | TSHR (0.39) | TSHRTYMPCA12CA9CA1 | |
| SCHEMBL14278404 | 0.81 | TSHR (0.52) | TSHRCA12CA1CA2CYP2D6 | |
| SCHEMBL2454848 | 0.81 | TSHR (0.52) | TSHRCA12CA1CA2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008131419-A2 | GLYCOCONJUGATES OF RNA INTERFERENCE AGENTS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | WO | disclosed |