Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.60 |
| ▸ | CYSLTR2 | Q9NS75 | 10/20 | 0.60 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.48 |
| ▸ | ABCC2 | Q92887 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.48 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8500070 | 0.90 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2ABCC1ABCC2KMT2A | |
| SCHEMBL9208597 | 0.90 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2ABCC1ABCC2KMT2A | |
| SCHEMBL8500066 | 0.90 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2ABCC1ABCC2KMT2A | |
| SCHEMBL9208589 | 0.90 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2ABCC1ABCC2KMT2A | |
| SCHEMBL4416695 | 0.87 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2ABCC1ABCC2KMT2A | |
| SCHEMBL8301924 | 0.87 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2KMT2AMEN1KDM4E | |
| SCHEMBL4416693 | 0.87 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2ABCC1ABCC2KMT2A | |
| SCHEMBL8301927 | 0.87 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2KMT2AMEN1KDM4E | |
| SCHEMBL4416755 | 0.87 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2ABCC1ABCC2KMT2A | |
| SCHEMBL4416752 | 0.87 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2ABCC1ABCC2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035379-A2 | PROCESS FOR AND INTERMEDIATES OF LEUKOTRIENE ANTAGONISTS | APTUIT LAURUS PRIVATE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |