Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | MYLK2 | Q9H1R3 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789183 | 0.82 | NPC1 (0.48) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL2789187 | 0.82 | NPC1 (0.48) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL2790132 | 0.79 | PIK3CD (0.45) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL2790134 | 0.79 | PIK3CD (0.45) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL4867602 | 0.76 | CDK1 (0.45) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL4871528 | 0.76 | CDK1 (0.45) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL4872082 | 0.75 | MAPT (0.46) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL2993824 | 0.75 | DYRK3 (0.39) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL4867476 | 0.74 | PIK3CD (0.46) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG | |
| SCHEMBL4877100 | 0.74 | PIK3CD (0.46) | PIK3CDPIM1CSNK2A2PIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885362-A2 | NOVEL CHEMICAL COMPOUNDS | Smithkline Beecham Corporation (US) | 2008-02-13 | — | — | EP | claimed |
| WO-2006127458-A2 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-11-30 | — | — | WO | claimed |