Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.72 |
| ▸ | SCARB1 | Q8WTV0 | 11/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565276 | 0.90 | MAPK14 (0.76) | MAPK14SCARB1SRCSYKLCK | |
| SCHEMBL1599582 | 0.90 | MAPK14 (0.77) | MAPK14SCARB1SRCSYKLCK | |
| SCHEMBL4944592 | 0.89 | MAPK14 (0.74) | MAPK14SCARB1SRCSYKGSK3A | |
| SCHEMBL4957803 | 0.89 | MAPK14 (0.63) | MAPK14SCARB1GSK3A | |
| SCHEMBL4964930 | 0.88 | MAPK14 (0.70) | MAPK14SCARB1SRCSYKLCK | |
| SCHEMBL4950811 | 0.88 | MAPK14 (0.72) | MAPK14SCARB1SRCSYKLCK | |
| SCHEMBL4946391 | 0.86 | MAPK14 (0.70) | MAPK14SCARB1 | |
| SCHEMBL4955134 | 0.85 | MAPK14 (0.68) | MAPK14SCARB1SRCSYKLCK | |
| SCHEMBL4419926 | 0.85 | MAPK14 (0.83) | MAPK14SCARB1SRCSYKLCK | |
| SCHEMBL1598842 | 0.84 | MAPK14 (0.81) | MAPK14SCARB1SRCSYKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089034-A2 | CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-07-24 | — | — | WO | disclosed |