Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CCL2 | P13500 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11348748 | 0.77 | BRD4 (0.41) | BRD4CCL2HTR2AHTR6ATM | |
| SCHEMBL20506900 | 0.75 | ATM (0.38) | BRD4CCL2HTR2AATM | |
| SCHEMBL230905 | 0.74 | BRD4 (0.36) | BRD4CCL2HTR2AATM | |
| SCHEMBL20506906 | 0.73 | ATM (0.40) | BRD4CCL2ATM | |
| SCHEMBL418352 | 0.73 | BRD4 (0.38) | BRD4CCL2HTR2AHTR6ATM | |
| SCHEMBL19452304 | 0.71 | BRD4 (0.35) | BRD4CCL2ATM | |
| SCHEMBL18645092 | 0.70 | BRD4 (0.34) | BRD4CCL2 | |
| SCHEMBL17284105 | 0.70 | BRD4 (0.36) | BRD4CCL2HTR2AATM | |
| Hydrochloric Acid SCHEMBL11111763 | 0.69 | BRD4 (0.35) | BRD4CCL2HTR2AATM | |
| SCHEMBL17234511 | 0.67 | BRD4 (0.34) | BRD4CCL2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112278-A2 | METHODS AND COMPOSITIONS FOR MODULATING INSULIN SECRETION AND GLUCOSE METABOLISM | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-09-18 | — | — | WO | disclosed |