Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 19/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14594930 | 0.91 | ALK (0.58) | ALK | |
| SCHEMBL14594956 | 0.87 | ALK (0.55) | ALK | |
| SCHEMBL14594934 | 0.81 | ALK (0.47) | ALK | |
| SCHEMBL14626816 | 0.80 | ALK (0.46) | ALKHTR1AHTR1B | |
| SCHEMBL14594932 | 0.80 | ALK (0.51) | ALK | |
| SCHEMBL14594931 | 0.79 | ALK (0.52) | ALK | |
| SCHEMBL14594933 | 0.79 | ERBB2 (0.47) | ALK | |
| SCHEMBL14594959 | 0.79 | ALK (0.45) | ALK | |
| SCHEMBL4962614 | 0.79 | CHRM2 (0.40) | ALKCHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL14594938 | 0.79 | ALK (0.51) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896472-A1 | ALPHA-CARBOLINES AS CDK-1 INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006131552-A1 | ALPHA-CARBOLINES AS CDK-1 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-12-14 | — | — | WO | disclosed |