Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960008 | 0.95 | BDKRB1 (0.77) | BDKRB1CYP3A4 | |
| SCHEMBL5006021 | 0.89 | BDKRB1 (0.58) | BDKRB1CYP3A4 | |
| SCHEMBL4959009 | 0.89 | BDKRB1 (0.76) | BDKRB1CYP3A4 | |
| SCHEMBL4957070 | 0.89 | BDKRB1 (0.61) | BDKRB1CYP3A4 | |
| SCHEMBL4957022 | 0.86 | BDKRB1 (0.81) | BDKRB1 | |
| SCHEMBL5010972 | 0.86 | BDKRB1 (0.60) | BDKRB1CYP3A4 | |
| SCHEMBL4957076 | 0.86 | BDKRB1 (0.77) | BDKRB1 | |
| SCHEMBL4958391 | 0.86 | BDKRB1 (0.66) | BDKRB1CYP3A4 | |
| SCHEMBL4958336 | 0.83 | BDKRB1 (0.60) | BDKRB1CYP3A4 | |
| SCHEMBL4957940 | 0.82 | BDKRB1 (1.00) | BDKRB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656355-B1 | PIPERAZINE DERIVATIVES AND METHODS OF USE | AMGEN INC (US) | 2008-03-12 | — | — | EP | claimed |
| EP-1878728-A2 | Derivatives of piperazine and higher homologues thereof for the treatment of inflammation-related disorders | Amgen Inc. (US) | 2008-01-16 | — | — | EP | claimed |
| EP-1878728-A2 | Derivatives of piperazine and higher homologues thereof for the treatment of inflammation-related disorders | Amgen Inc. (US) | 2008-01-16 | — | — | EP | disclosed |