Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13213913 | 0.90 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL2943453 | 0.89 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL2942732 | 0.87 | BDKRB1 (0.75) | BDKRB1 | |
| SCHEMBL4959064 | 0.86 | BDKRB1 (0.75) | BDKRB1 | |
| SCHEMBL13214200 | 0.86 | BDKRB1 (0.82) | BDKRB1 | |
| SCHEMBL12477012 | 0.85 | BDKRB1 (0.71) | BDKRB1 | |
| SCHEMBL3621477 | 0.84 | BDKRB1 (0.73) | BDKRB1 | |
| SCHEMBL12476815 | 0.84 | BDKRB1 (0.70) | BDKRB1 | |
| SCHEMBL13213929 | 0.84 | BDKRB1 (0.88) | BDKRB1 | |
| SCHEMBL13214202 | 0.84 | BDKRB1 (0.88) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893579-B1 | 1-HYDROXYCYCLOALKANECARBOXAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | MERCK SHARP & DOHME (US) | 2013-05-01 | — | — | EP | disclosed |
| EP-1893579-A1 | 1-HYDROXYCYCLOALKANECARBOXAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | Merck & Co., Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006132837-A1 | l-HYDROXYCYCLOALKANECARBOXAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | MERCK & CO., INC. (US) | 2006-12-14 | — | — | WO | disclosed |