Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 20/20 | 0.53 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3573125 | 1.00 | CNR1 (0.53) | CNR1CNR2KCNH2 | |
| SCHEMBL3573123 | 1.00 | CNR1 (0.53) | CNR1CNR2KCNH2 | |
| Hydrochloric Acid SCHEMBL3577766 | 0.99 | CNR1 (0.52) | CNR1CNR2KCNH2 | |
| Hydrochloric Acid SCHEMBL3577764 | 0.99 | CNR1 (0.52) | CNR1CNR2KCNH2 | |
| SCHEMBL3561596 | 0.83 | CNR1 (0.62) | CNR1CNR2KCNH2 | |
| SCHEMBL3568204 | 0.81 | CNR1 (0.67) | CNR1CNR2KCNH2 | |
| SCHEMBL3577716 | 0.79 | CNR1 (0.60) | CNR1CNR2KCNH2 | |
| SCHEMBL3567617 | 0.77 | CNR1 (0.50) | CNR1CNR2 | |
| SCHEMBL3569809 | 0.77 | CNR1 (0.50) | CNR1CNR2 | |
| SCHEMBL3567616 | 0.77 | CNR1 (0.50) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725232-B1 | (INDOL-3-YL)-HETEROCYCLE DERIVATIVES AS AGONISTS OF THE CANNABINOID CB1 RECEPTOR | ORGANON NV (NL) | 2008-01-23 | — | — | EP | disclosed |