Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10974094 | 0.91 | PTGDR2 (0.61) | PTGDR2AKR1B1 | |
| SCHEMBL4962605 | 0.90 | PTGDR2 (0.62) | PTGDR2AKR1B1 | |
| SCHEMBL4960661 | 0.87 | PTGDR2 (0.51) | PTGDR2AKR1B1 | |
| SCHEMBL4961232 | 0.86 | PTGDR2 (0.63) | PTGDR2AKR1B1 | |
| SCHEMBL4958399 | 0.85 | AKR1B1 (0.51) | PTGDR2AKR1B1 | |
| SCHEMBL4962400 | 0.85 | PTGDR2 (0.53) | PTGDR2AKR1B1 | |
| SCHEMBL4961366 | 0.84 | PTGDR2 (0.61) | PTGDR2AKR1B1 | |
| SCHEMBL4960185 | 0.81 | PTGDR2 (0.63) | PTGDR2AKR1B1 | |
| SCHEMBL4394762 | 0.81 | PTGDR2 (0.67) | PTGDR2 | |
| SCHEMBL10978203 | 0.81 | SCN9A (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891075-A1 | TRICYCLIC SPIRO DERIVATIVES AS CRTH2 MODULATORS | LABORATOIRES SERONO S.A. (CH) | 2008-02-27 | — | — | EP | claimed |
| WO-2006125784-A1 | TRICYCLIC SPIRO DERIVATIVES AS CRTH2 MODULATORS | LABORATOIRES SERONO S.A. (CH) | 2006-11-30 | — | — | WO | claimed |