Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2449230 | 0.88 | PTGDR2 (0.61) | PTGDR2 | |
| SCHEMBL4959540 | 0.87 | PTGDR2 (0.60) | PTGDR2 | |
| SCHEMBL4962637 | 0.81 | PTGDR2 (0.61) | PTGDR2 | |
| SCHEMBL2442799 | 0.78 | PTGDR2 (0.70) | PTGDR2 | |
| SCHEMBL2449199 | 0.77 | PTGDR2 (0.69) | PTGDR2 | |
| SCHEMBL4962043 | 0.75 | PTGDR2 (0.58) | PTGDR2 | |
| SCHEMBL2449786 | 0.74 | PTGDR2 (0.59) | PTGDR2 | |
| SCHEMBL2444877 | 0.73 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL2444000 | 0.72 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL2449429 | 0.71 | PTGDR2 (0.62) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871374-A2 | 2,3 SUBSTITUTED PYRAZINE SULFONAMIDES AS INHIBITORS OF CRTH2 | Laboratoires Serono SA (CH) | 2008-01-02 | — | — | EP | claimed |
| WO-2006111560-A2 | 2,3 SUBSTITUTED PYRAZINE SULFONAMIDES AS INHIBITORS OF CRTH2 | LABORATOIRES SERONO S.A. (CH) | 2006-10-26 | — | — | WO | claimed |
| EP-1871374-A2 | 2,3 SUBSTITUTED PYRAZINE SULFONAMIDES AS INHIBITORS OF CRTH2 | Laboratoires Serono SA (CH) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006111560-A2 | 2,3 SUBSTITUTED PYRAZINE SULFONAMIDES AS INHIBITORS OF CRTH2 | LABORATOIRES SERONO S.A. (CH) | 2006-10-26 | — | — | WO | disclosed |