Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610924 | 1.00 | EPHX2 (0.68) | EPHX2KMT2ARAB9AHSD11B1TDP1 | |
| SCHEMBL610923 | 1.00 | EPHX2 (0.68) | EPHX2KMT2ARAB9AHSD11B1TDP1 | |
| SCHEMBL5247365 | 0.93 | EPHX2 (0.79) | EPHX2KMT2ARAB9AHSD11B1MEN1 | |
| SCHEMBL613325 | 0.92 | EPHX2 (0.81) | EPHX2KMT2ARAB9AHSD11B1MEN1 | |
| SCHEMBL611926 | 0.90 | KMT2A (0.62) | EPHX2KMT2ARAB9AHSD11B1TDP1 | |
| SCHEMBL611925 | 0.90 | KMT2A (0.62) | EPHX2KMT2ARAB9AHSD11B1TDP1 | |
| SCHEMBL4960581 | 0.90 | KMT2A (0.62) | EPHX2KMT2ARAB9AHSD11B1TDP1 | |
| SCHEMBL612268 | 0.88 | KMT2A (0.62) | EPHX2KMT2ARAB9AHSD11B1TDP1 | |
| SCHEMBL612269 | 0.88 | KMT2A (0.62) | EPHX2KMT2ARAB9AHSD11B1TDP1 | |
| SCHEMBL4960532 | 0.88 | KMT2A (0.62) | EPHX2KMT2ARAB9AHSD11B1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758580-A4 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-16 | — | — | EP | claimed |
| EP-1758580-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2006012226-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | claimed |
| EP-1758580-A4 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-16 | — | — | EP | disclosed |
| EP-1758580-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006012226-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |