Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2929900 | 0.84 | POLB (0.61) | POLBHSD17B10KMT2AL3MBTL1MAPT | |
| SCHEMBL4745187 | 0.80 | POLB (0.45) | POLBHSD17B10KMT2AL3MBTL1MAPT | |
| SCHEMBL9118538 | 0.80 | POLB (0.59) | POLBHSD17B10KMT2AL3MBTL1MAPT | |
| SCHEMBL15953118 | 0.79 | POLB (0.55) | POLBHSD17B10KMT2AL3MBTL1MAPT | |
| SCHEMBL16670318 | 0.79 | POLB (0.55) | POLBHSD17B10KMT2AL3MBTL1MAPT | |
| SCHEMBL8373225 | 0.78 | POLB (0.53) | POLBHSD17B10KMT2AL3MBTL1MAPT | |
| SCHEMBL16670248 | 0.76 | POLB (0.52) | POLBHSD17B10KMT2AL3MBTL1MAPT | |
| SCHEMBL367099 | 0.75 | POLB (0.56) | POLBHSD17B10KMT2AL3MBTL1MAPT | |
| SCHEMBL1576666 | 0.74 | POLB (0.49) | POLBHSD17B10KMT2AL3MBTL1MAPT | |
| SCHEMBL17223627 | 0.74 | POLB (0.49) | POLBHSD17B10KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891106-A2 | NOVEL COMPOUNDS AS GLP-I AGONISTS | CADILA HEALTHCARE LTD. (IN) | 2008-02-27 | — | — | EP | claimed |
| WO-2007017892-A2 | NOVEL COMPOUNDS AS GLP-I AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2007-02-15 | — | — | WO | claimed |
| EP-1891106-A2 | NOVEL COMPOUNDS AS GLP-I AGONISTS | CADILA HEALTHCARE LTD. (IN) | 2008-02-27 | — | — | EP | disclosed |
| WO-2007017892-A2 | NOVEL COMPOUNDS AS GLP-I AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |