Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 11/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17186372 | 0.99 | PNP (0.97) | PNPKDM4ESMN1; SMN2LMNATSHR | |
| Hydrochloric Acid SCHEMBL17186285 | 0.87 | PNP (0.77) | PNPFGFR1FGFR2 | |
| SCHEMBL5265323 | 0.81 | PNP (0.68) | PNPKDM4ESMN1; SMN2LMNATSHR | |
| SCHEMBL5084758 | 0.81 | PNP (0.67) | PNPKDM4EFGFR1FGFR2 | |
| SCHEMBL9960811 | 0.80 | PNP (0.71) | PNPKDM4EFGFR1FGFR2 | |
| SCHEMBL4967481 | 0.79 | PNP (0.65) | PNPKDM4EFGFR1FGFR2 | |
| SCHEMBL9434519 | 0.78 | PNP (0.64) | PNPFGFR1FGFR2 | |
| SCHEMBL4963414 | 0.78 | PNP (0.64) | PNPKDM4EFGFR1FGFR2 | |
| SCHEMBL3300185 | 0.78 | PNP (0.64) | PNPKDM4EFGFR1FGFR2 | |
| SCHEMBL18248 | 0.78 | PNP (1.00) | PNPFGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4054057-B2 | — | — | 2008-02-27 | — | — | JP | claimed |
| CN-1948313-A | Preparation method of tiemoazoleamine-8-carboxylic acid water soluble derivative, anticancer activity and application in preparing anticancer medicine | TIANJIN BEIFANG SCIENCE AND TE (CN) | 2007-04-18 | — | — | CN | claimed |
| EP-0702683-B1 | 06-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER REC TECH LTD (GB) | 2003-09-17 | — | — | EP | claimed |
| WO-1994029312-A1 | O6-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1994-12-22 | — | — | WO | claimed |
| CN-1948313-A | Preparation method of tiemoazoleamine-8-carboxylic acid water soluble derivative, anticancer activity and application in preparing anticancer medicine | TIANJIN BEIFANG SCIENCE AND TE (CN) | 2007-04-18 | — | — | CN | disclosed |
| EP-0702683-B1 | 06-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER REC TECH LTD (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-1994029312-A1 | O6-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |