Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | PYGL | P06737 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1572442 | 0.94 | MEN1 (0.76) | TP53MEN1KMT2AALDH1A1CES2 | |
| SCHEMBL31103641 | 0.94 | MEN1 (0.76) | TP53MEN1KMT2AALDH1A1CES2 | |
| Methyl Benzoate SCHEMBL29102092 | 0.92 | MEN1 (0.71) | TP53MEN1KMT2AALDH1A1CES2 | |
| SCHEMBL27858189 | 0.92 | MEN1 (0.74) | TP53MEN1KMT2AALDH1A1CES2 | |
| Methane SCHEMBL28043489 | 0.92 | MEN1 (0.74) | TP53MEN1KMT2AALDH1A1CES2 | |
| Fluoride SCHEMBL28307367 | 0.92 | MEN1 (0.74) | TP53MEN1KMT2AALDH1A1CES2 | |
| Ammonia Solution, Strong SCHEMBL27704150 | 0.92 | MEN1 (0.74) | TP53MEN1KMT2AALDH1A1CES2 | |
| Dinitrophenylene SCHEMBL27567750 | 0.88 | MEN1 (0.64) | TP53MEN1KMT2AALDH1A1CES2 | |
| Methyl Alcohol SCHEMBL27634070 | 0.87 | TP53 (0.93) | TP53MEN1KMT2AALDH1A1CES2 | |
| Benzenethiol SCHEMBL28085230 | 0.87 | MEN1 (0.64) | TP53MEN1KMT2AALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888546-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006125805-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2006-11-30 | — | — | WO | disclosed |