Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10376304 | 0.83 | — | — | |
| SCHEMBL58 | 0.83 | — | — | |
| SCHEMBL4011609 | 0.83 | BRD4 (0.30) | — | |
| SCHEMBL2201542 | 0.83 | — | — | |
| Ammonia Solution, Strong SCHEMBL28443159 | 0.80 | — | — | |
| SCHEMBL30280996 | 0.80 | — | — | |
| SCHEMBL4511932 | 0.80 | — | — | |
| Fluoride SCHEMBL7176780 | 0.80 | — | — | |
| Bromide SCHEMBL4047360 | 0.80 | — | — | |
| SCHEMBL28948472 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102088849-A | A1Allosteric enhancers of adenosine receptors | KING PHARMACEUTICALS RES & DEV | 2011-06-08 | — | — | CN | disclosed |
| EP-1877391-A1 | PRO-DRUGS OF N-THIAZOL-2YL-BENZAMIDE DERIVATIVES | H. Lundbeck A/S (DK) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006114093-A1 | PRO-DRUGS OF N-THIAZOL-2YL-BENZAMIDE DERIVATIVES | H. LUNDBECK A/S (DK) | 2006-11-02 | — | — | WO | disclosed |