Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12300762 | 0.82 | KDM4E (0.32) | CTSAACHEKDM4EALDH1A1POLB | |
| SCHEMBL12300764 | 0.80 | KDM4E (0.33) | KDM4EALDH1A1POLB | |
| SCHEMBL17485083 | 0.76 | — | — | |
| SCHEMBL14460147 | 0.75 | — | — | |
| SCHEMBL5582435 | 0.75 | — | — | |
| SCHEMBL894405 | 0.70 | CTSA (0.37) | CTSAACHEKDM4EALDH1A1POLB | |
| SCHEMBL13538551 | 0.69 | HRH3 (0.35) | — | |
| SCHEMBL13537863 | 0.67 | TSHR (0.40) | — | |
| SCHEMBL4963595 | 0.67 | CTSA (0.34) | CTSAACHEKDM4EALDH1A1POLB | |
| SCHEMBL525985 | 0.66 | CTSA (0.48) | CTSAACHEKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-A4 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2008-03-05 | — | — | EP | disclosed |
| EP-1715873-A1 | NUCLEOSIDE PHOSPHONATE DERIVATIVES USEFUL IN THE TREATMENT OF HIV INFECTIONS | LG Life Sciences Ltd. (KR) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005079812-A1 | NUCLEOSIDE PHOSPHONATE DERIVATIVES USEFUL IN THE TREATMENT OF HIV INFECTIONS | LG LIFE SCIENCES LTD. (KR) | 2005-09-01 | — | — | WO | disclosed |
| EP-1358198-A1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG Chem Investment, Ltd. (KR) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002057288-A1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD. (KR) | 2002-07-25 | — | — | WO | disclosed |