⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854401 | 0.89 | — | — | |
| SCHEMBL6854406 | 0.89 | — | — | |
| SCHEMBL23718157 | 0.65 | — | — | |
| SCHEMBL8061141 | 0.62 | — | — | |
| SCHEMBL17859700 | 0.62 | — | — | |
| SCHEMBL8740079 | 0.60 | — | — | |
| SCHEMBL2423908 | 0.60 | — | — | |
| SCHEMBL9792786 | 0.58 | — | — | |
| SCHEMBL19760472 | 0.58 | — | — | |
| SCHEMBL23001656 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1250393-A | — | — | None | — | — | JP | disclosed |
| EP-0638089-B2 | SYNTHESIS OF DIVERSE AND USEFUL COLLECTIONS OF OLIGONUCLEOTIDES | UNIV JOHNS HOPKINS (US) | 2008-03-05 | — | — | EP | disclosed |
| EP-0638089-B1 | SYNTHESIS OF DIVERSE AND USEFUL COLLECTIONS OF OLIGONUCLEOTIDES | UNIV JOHNS HOPKINS (US) | 2001-03-14 | — | — | EP | disclosed |
| US-5869644-A | Synthesis of diverse and useful collections of oligonucleotidies | THE JOHNS HOPKINS UNIVERSITY (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0541693-B1 | LARGE COMB-TYPE BRANCHED POLYNUCLEOTIDES | CHIRON CORP (US) | 1998-12-09 | — | — | EP | disclosed |
| US-5703218-A | USEFUL IN BIOSYNTHESIS | CHIRON CORPORATION (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0330221-B1 | End labeled nuceotide probe | ENZO BIOCHEM INC (US) | 1997-10-29 | — | — | EP | disclosed |
| EP-0783000-A2 | Method for synthesizing end labeled nucleotide probes | ENZO BIOCHEM, INC. (US) | 1997-07-09 | — | — | EP | disclosed |
| US-5639873-A | Oligothionucleotides | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1997-06-17 | — | — | US | disclosed |
| EP-0543906-B1 | HYDROXYL-PROTECTING GROUPS ORTHOGONALLY REMOVABLE BY REDUCTION AND THEIR USE IN THE CHEMICAL SYNTHESIS OF OLIGONUCLEOTIDES | CHIRON CORP (US) | 1997-03-26 | — | — | EP | disclosed |
| JP-H01250393-A | SYNTHESIS OF OLIGONUCREOTIDE IN WHICH AMINO GROUP IS INTRODUCED | CALIFORNIA INST OF TECHNOL | 1989-10-05 | — | — | JP | disclosed |
| US-4849513-A | Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1989-07-18 | — | — | US | disclosed |
| US-4818681-A | Fast and specific immobilization of nucleic acids to solid supports | MOLECULAR DIAGNOSTICS, INC. (US) | 1989-04-04 | — | — | US | disclosed |
| EP-0270651-A4 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. | CALIFORNIA INST OF TECHN (US) | 1989-03-29 | — | — | EP | disclosed |
| US-4808520-A | HYBRIDIZING WITH NUCLEIC ACID, THEN WITH NUCLEOSIDE TRIPHOSPHATE IN PRESENCE OF ENZYME | MOLECULAR DIAGNOSTICS, INC. (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0270651-A1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. | CALIFORNIA INST OF TECHN (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1988000201-A1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY, INC. (US) | 1988-01-14 | — | — | WO | disclosed |
| EP-0235301-A1 | PYRIDOPYRIMIDINE NUCLEOTIDE DERIVATIVES | TEIJIN LIMITED (JP) | 1987-09-09 | — | — | EP | disclosed |
| EP-0194545-A2 | Labelling of oligonucleotides | MOLECULAR DIAGNOSTICS, INC. (US) | 1986-09-17 | — | — | EP | disclosed |
| EP-0192197-A2 | Fast and specific immobilization of nucleic acids to solid supports | MOLECULAR DIAGNOSTICS, INC. (US) | 1986-08-27 | — | — | EP | disclosed |