SCHEMBL4964534

SCHEMBL4964534

C=CC(Cl)C(=O)C(Cl)C=C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.32
ALDH1A1 P00352 2/20 0.30
TSHR P16473 1/20 0.30
FGFR4 P22455 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2354584 0.78
SCHEMBL760196 0.78
SCHEMBL11749869 0.78
SCHEMBL10704756 0.75
SCHEMBL16319261 0.75
Hydrochloric Acid SCHEMBL2354586 0.75
Ammonia Solution, Strong SCHEMBL6461149 0.75
SCHEMBL3085891 0.71
SCHEMBL5872870 0.71
SCHEMBL28151593 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7053055-B2 Compounds of unstable DP IV-inhibitors PROSIDION LTD. (GB) 2006-05-30 US claimed
US-20010020006-A1 Compounds of unstable DP IV-inhibitors PROSIDION LIMITED (GB) 2001-09-06 US claimed
EP-1496092-B1 Resin composition for metal sheet coating, resin film employing it, resin-coated metal sheet and resin-coated metal container NIPPON STEEL CORP (JP) 2008-02-20 EP disclosed
US-7312276-B2 Resin composition for metal sheet coating, resin film employing it, resin-coated metal sheet and resin-coated metal container NIPPON STEEL CORPORATION (JP) 2007-12-25 US disclosed
US-7053055-B2 Compounds of unstable DP IV-inhibitors PROSIDION LTD. (GB) 2006-05-30 US disclosed
EP-1035182-B1 COATING RESIN COMPOSITION FOR METAL SHEETS, AND RESIN FILMS, RESIN-COATED METAL SHEETS AND RESIN-COATED METAL VESSELS EACH MADE BY USING THE COMPOSITION NIPPON STEEL CORP (JP) 2005-09-14 EP disclosed
EP-1496092-A1 Resin composition for metal sheet coating, resin film employing it, resin-coated metal sheet and resin-coated metal container NIPPON STEEL CORPORATION (JP) 2005-01-12 EP disclosed
US-20040198907-A1 Resin composition for metal sheet coating, resin film employing it, resin-coated metal sheet and resin-coated metal container NIPPON STEEL CORPORATION (JP) 2004-10-07 US disclosed
US-6783825-B1 ELASTOMER FINELY DISPERSED IN POLYESTER AND CAPSULATED BY VINYL POLYMER; BEVERAGE CANS NIPPON STEEL CORPORATION (JP) 2004-08-31 US disclosed
US-20010020006-A1 Compounds of unstable DP IV-inhibitors PROSIDION LIMITED (GB) 2001-09-06 US disclosed
EP-1035182-A1 COATING RESIN COMPOSITION FOR METAL SHEETS, AND RESIN FILMS, RESIN-COATED METAL SHEETS AND RESIN-COATED METAL VESSELS EACH MADE BY USING THE COMPOSITION NIPPON STEEL CORPORATION (JP) 2000-09-13 EP disclosed
US-3969520-A 2-Amino-4[2-(1-lower alkyl-5-nitro-2-imidiazolyl)vinyl]pyrimidines for treating protozoal and bacterial infections ISTITUTO CHEMIOTERAPICO ITALIANO S.P.A. (IT) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010020006-A1 Compounds of unstable DP IV-inhibitors DPP4, DPP3, SLC2A4 LMNA 2677/4885ALDH1A1 565/4885TSHR 4726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.