Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 6/20 | 0.40 |
| ▸ | F10 | P00742 | 6/20 | 0.40 |
| ▸ | PLG | P00747 | 5/20 | 0.40 |
| ▸ | PLAU | P00749 | 5/20 | 0.40 |
| ▸ | PLAT | P00750 | 5/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.40 |
| ▸ | F7 | P08709 | 3/20 | 0.39 |
| ▸ | F3 | P13726 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961386 | 0.94 | HDAC6 (0.47) | HDAC6F2F10PLGPLAU | |
| SCHEMBL4963266 | 0.90 | HDAC6 (0.47) | HDAC6F2F10PLGPLAU | |
| SCHEMBL4965597 | 0.90 | HDAC6 (0.47) | HDAC6F2F10PLGPLAU | |
| SCHEMBL1509621 | 0.89 | HDAC6 (0.41) | HDAC6TAS1R3TAS1R1F2F10 | |
| SCHEMBL4963532 | 0.85 | HDAC6 (0.50) | HDAC6F2F10PLGPLAU | |
| SCHEMBL14091703 | 0.84 | HDAC6 (0.39) | HDAC6TAS1R3TAS1R1IKBKBHDAC3 | |
| SCHEMBL1509572 | 0.83 | HDAC6 (0.40) | HDAC6F2F10PLGPLAU | |
| SCHEMBL4963154 | 0.81 | HDAC6 (0.60) | HDAC6F2F10PLGPLAU | |
| SCHEMBL4965539 | 0.80 | HDAC6 (0.61) | HDAC6F2F10PLGPLAU | |
| SCHEMBL1509537 | 0.80 | HDAC6 (0.41) | HDAC6F2F10PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207635-A1 | Heterocyclic compounds useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders | CHEMBRIDGE CORPORATION | 2008-08-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207635-A1 | Heterocyclic compounds useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders | LCK, MALT1, MYD88 | HDAC6 541/4885TAS1R3 3078/4885TAS1R1 3023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.