Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20731384 | 1.00 | GRM2 (1.00) | GRM2GRM3 | |
| SCHEMBL20722244 | 1.00 | GRM2 (1.00) | GRM2GRM3 | |
| SCHEMBL22130855 | 0.84 | GRM2 (0.73) | GRM2GRM3 | |
| SCHEMBL22130854 | 0.82 | GRM2 (0.70) | GRM2GRM3 | |
| SCHEMBL4968500 | 0.79 | GRM2 (0.65) | GRM2GRM3 | |
| SCHEMBL20722249 | 0.78 | GRM2 (0.62) | GRM2GRM3 | |
| SCHEMBL23718799 | 0.73 | GRM2 (0.74) | GRM2GRM3 | |
| SCHEMBL4967945 | 0.73 | GRM2 (0.63) | GRM2GRM3 | |
| SCHEMBL4964629 | 0.73 | GRM2 (0.74) | GRM2GRM3 | |
| SCHEMBL16713408 | 0.72 | GRM2 (0.55) | GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689327-B2 | Prodrug amino acid derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2020-06-23 | — | — | US | disclosed |
| US-20190337887-A1 | PRODRUG OF AMINO ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2019-11-07 | — | — | US | disclosed |
| EP-1459765-B1 | 6-FLUOROBICYCLO 3.1.0 HEXANE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2008-08-20 | — | — | EP | disclosed |
| US-7157594-B2 | 6-Fluorobicyclo[3.1.0]hexane derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |
| US-20050119345-A1 | 6-Fluorobicyclo[3.1.0]hexane derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10689327-B2 | Prodrug amino acid derivative | GRIN2A, SLC1A2, SLC1A1 | GRM2 12/4885GRM3 26/4885 |
| US-20190337887-A1 | PRODRUG OF AMINO ACID DERIVATIVE | GRIN2A, SLC1A2, SLC1A1 | GRM2 13/4885GRM3 28/4885 |
| US-20050119345-A1 | 6-Fluorobicyclo[3.1.0]hexane derivatives | GRM1, GRM2, GRM6 | GRM2 2/4885GRM3 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.