Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443754 | 0.91 | — | — | |
| SCHEMBL195392 | 0.91 | — | — | |
| SCHEMBL441789 | 0.91 | — | — | |
| SCHEMBL28115397 | 0.88 | — | — | |
| SCHEMBL27750069 | 0.88 | — | — | |
| Hexylene Glycol SCHEMBL83192 | 0.80 | TDP1 (0.40) | TDP1MAPK1CYP1A2CYP3A4CYP2C9 | |
| Hexylene Glycol SCHEMBL8519090 | 0.80 | TDP1 (0.40) | TDP1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28815523 | 0.79 | ACACB (0.37) | TDP1 | |
| Ethylene Glycol SCHEMBL8467555 | 0.79 | TSHR (0.39) | TDP1TSHR | |
| Hexylene Glycol SCHEMBL10667144 | 0.74 | TDP1 (0.35) | TDP1MAPK1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10912863-B2 | Tissue products derived from animals lacking any expression of functional alpha 1, 3 galactosyltransferase | REVIVICOR, INC. (US) | 2021-02-09 | — | — | US | disclosed |
| US-20190111180-A1 | Tissue Products Derived from Animals Lacking any Expression of Functional Alpha 1, 3 Galactosyltransferase | REVIVICOR, INC. | 2019-04-18 | — | — | US | disclosed |
| US-10130737-B2 | Tissue products derived from animals lacking any expression of functional alpha 1, 3 galactosyltransferase | REVIVICOR, INC. (US) | 2018-11-20 | — | — | US | disclosed |
| EP-2433492-B1 | Tissue products derived from animals lacking any expression of functional alpha 1,3 galactosyltransferase | REVIVICOR INC (US) | 2018-04-25 | — | — | EP | disclosed |
| US-20150182664-A1 | Tissue Products Derived from Animals Lacking any Expression of Functional Alpha 1, 3 Galactosyltransferase | REVIVICOR, INC. (US) | 2015-07-02 | — | — | US | disclosed |
| EP-1734814-B1 | TISSUE PRODUCTS DERIVED FROM ANIMALS LACKING ANY EXPRESSION OF FUNCTIONAL ALPHA 1,3 GALACTOSYLTRANSFERASE | REVIVICOR INC (US) | 2015-01-21 | — | — | EP | disclosed |
| US-20120282226-A1 | Tissue Products Derived From Animals Lacking Any Expression of Functional Alpha 1, 3 Galactosyltransferase | AYARES DAVID (US) | 2012-11-08 | — | — | US | disclosed |
| EP-2433492-A1 | Tissue products derived from animals lacking any expression of functional alpha 1,3 galactosyltransferase | Revivicor Inc. (US) | 2012-03-28 | — | — | EP | disclosed |
| US-8106251-B2 | Tissue products derived from porcine animals lacking any expression of functional alpha 1,3 galactosyltransferase | REVIVICOR, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| EP-1734814-A4 | TISSUE PRODUCTS DERIVED FROM ANIMALS LACKING ANY EXPRESSION OF FUNCTIONAL ALPHA 1,3 GALACTOSYLTRANSFERASE | REVIVICOR INC (US) | 2009-08-26 | — | — | EP | disclosed |
| EP-1734814-A2 | TISSUE PRODUCTS DERIVED FROM ANIMALS LACKING ANY EXPRESSION OF FUNCTIONAL ALPHA 1,3 GALACTOSYLTRANSFERASE | REVIVICOR, INC. (US) | 2006-12-27 | — | — | EP | disclosed |
| US-20050260176-A1 | Tissue products derived from animals lacking any expression of functional alpha 1,3 galactosyltransferase | REVIVICOR, INC. (US) | 2005-11-24 | — | — | US | disclosed |
| WO-2005089411-A2 | TISSUE PRODUCTS FROM ANIMALS LACKING FUNCTIONAL ALPHA 1,3 GALACTOSYL TRANSFERASE | REVIVICOR, INC. (US) | 2005-09-29 | — | — | WO | disclosed |