Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203370 | 0.88 | PARP1 (0.67) | PARP1 | |
| SCHEMBL2763788 | 0.83 | PARP1 (0.65) | PARP1TSHR | |
| SCHEMBL13377699 | 0.78 | PARP1 (0.59) | PARP1 | |
| SCHEMBL2763303 | 0.76 | PARP1 (0.75) | PARP1 | |
| SCHEMBL2763098 | 0.76 | PARP1 (0.77) | PARP1 | |
| SCHEMBL13377548 | 0.76 | PARP1 (0.77) | PARP1 | |
| SCHEMBL13377702 | 0.76 | PARP1 (0.77) | PARP1 | |
| SCHEMBL8274291 | 0.76 | PARP1 (0.77) | PARP1 | |
| SCHEMBL29496073 | 0.76 | PARP1 (0.77) | PARP1 | |
| SCHEMBL2763527 | 0.75 | PARP1 (0.90) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1722797-A4 | ISOQUINOLINE DERIVATIVES AND METHODS OF USE THEREOF | INOTEK PHARMACEUTICALS CORP (US) | 2008-03-19 | — | — | EP | disclosed |
| EP-1722797-A1 | ISOQUINOLINE DERIVATIVES AND METHODS OF USE THEREOF | Inotek Pharmaceuticals Corporation (US) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005082368-A1 | ISOQUINOLINE DERIVATIVES AND METHODS OF USE THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2005-09-09 | — | — | WO | disclosed |