Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 6/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.45 |
| ▸ | DRD4 | P21917 | 5/20 | 0.45 |
| ▸ | DRD3 | P35462 | 5/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4964947 | 0.90 | GSK3B (0.51) | CHEK2CARM1HDAC6PDCD1CD274 | |
| SCHEMBL1509575 | 0.90 | CHEK2 (0.49) | CHEK2BCHEACHECARM1DRD2 | |
| SCHEMBL4964897 | 0.88 | CARM1 (0.51) | CHEK2CARM1HDAC6 | |
| SCHEMBL14090462 | 0.82 | GSK3B (0.49) | CHEK2CARM1DRD2DRD3HDAC6 | |
| SCHEMBL12834022 | 0.81 | CHEK2 (0.47) | CHEK2BCHEACHEHDAC6 | |
| SCHEMBL1509636 | 0.81 | GSK3B (0.56) | CHEK2CARM1 | |
| SCHEMBL14090464 | 0.80 | GSK3B (0.47) | CHEK2CARM1HDAC6 | |
| SCHEMBL14090453 | 0.79 | MCHR1 (0.48) | CHEK2CARM1DRD2DRD4 | |
| SCHEMBL4964920 | 0.78 | CARM1 (0.48) | CARM1HDAC6 | |
| SCHEMBL4963154 | 0.78 | HDAC6 (0.60) | CARM1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207635-A1 | Heterocyclic compounds useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders | CHEMBRIDGE CORPORATION | 2008-08-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207635-A1 | Heterocyclic compounds useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders | LCK, MALT1, MYD88 | CHEK2 330/4885BCHE 4092/4885ACHE 4426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.