Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | ENO1 | P06733 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4965090 | 1.00 | DPP4 (0.78) | DPP4CYP3A4TSHRTDP1MAPT | |
| Hydrochloric Acid SCHEMBL387479 | 0.98 | DPP4 (0.75) | DPP4CYP3A4TSHRTDP1MAPT | |
| Hydrochloric Acid SCHEMBL387480 | 0.98 | DPP4 (0.75) | DPP4CYP3A4TSHRTDP1MAPT | |
| SCHEMBL4963520 | 0.94 | DPP4 (0.75) | DPP4CYP3A4TSHRTDP1MAPT | |
| SCHEMBL4964366 | 0.94 | DPP4 (0.75) | DPP4CYP3A4TSHRTDP1MAPT | |
| SCHEMBL4967581 | 0.88 | DPP4 (1.00) | DPP4CYP3A4TSHRTDP1MAPT | |
| SCHEMBL4966678 | 0.88 | DPP4 (1.00) | DPP4CYP3A4TSHRTDP1MAPT | |
| SCHEMBL4990086 | 0.82 | DPP4 (0.57) | DPP4CYP3A4TSHRTDP1MAPT | |
| SCHEMBL4966452 | 0.78 | DPP4 (0.54) | DPP4CYP3A4TSHRTDP1MAPT | |
| SCHEMBL4991853 | 0.77 | DPP4 (0.48) | DPP4TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489088-B1 | NOVEL ALPHA-AMINO-N-(DIAMINOPHOSPHINYL)LACTAM DERIVATIVE | NIPPON KAYAKU KK (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-7348318-B2 | α-Amino-N-(diaminophosphinyl)lactam derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2008-03-25 | — | — | US | disclosed |
| US-20050164989-A1 | Novel $g(a)-amino-n-(diaminophosphinyl) lactam derivative | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2005-07-28 | — | — | US | disclosed |
| EP-1489088-A1 | NOVEL ALPHA-AMINO-N-(DIAMINOPHOSPHINYL)LACTAM DERIVATIVE | Nippon Kayaku Kabushiki Kaisha (JP) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050164989-A1 | Novel $g(a)-amino-n-(diaminophosphinyl) lactam derivative | DNPEP, PEPD, ANPEP | DPP4 8/4885CYP3A4 3736/4885TSHR 4295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.