⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18811995 | 1.00 | — | — | |
| SCHEMBL4965456 | 1.00 | — | — | |
| SCHEMBL19780334 | 0.79 | — | — | |
| SCHEMBL12320166 | 0.77 | — | — | |
| SCHEMBL14625691 | 0.77 | — | — | |
| SCHEMBL19780741 | 0.77 | — | — | |
| SCHEMBL28858723 | 0.77 | KDM4E (0.39) | — | |
| SCHEMBL19487260 | 0.75 | — | — | |
| SCHEMBL14520485 | 0.75 | — | — | |
| SCHEMBL14945608 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045983-A | Preparing method of Afatinib | 苏州富士莱医药股份有限公司 | 2016-10-26 | — | — | CN | claimed |
| CN-113825816-B | Two-component adhesive composition, articles made therefrom, and method of making the same | 陶氏环球技术有限责任公司 | 2023-11-24 | — | — | CN | disclosed |
| US-20220177753-A1 | TWO-COMPONENT ADHESIVE COMPOSITIONS, ARTICLES PREPARED WITH SAME AND PREPARATION METHODS THEREOF | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-06-09 | — | — | US | disclosed |
| EP-3969530-A1 | TWO-COMPONENT ADHESIVE COMPOSITIONS, ARTICLES PREPARED WITH SAME AND PREPARATION METHODS THEREOF | Dow Global Technologies LLC (US) | 2022-03-23 | — | — | EP | disclosed |
| CN-113825816-A | Two-part adhesive composition, articles made therefrom, and method of making same | 陶氏环球技术有限责任公司 | 2021-12-21 | — | — | CN | disclosed |
| WO-2020227963-A1 | TWO-COMPONENT ADHESIVE COMPOSITIONS, ARTICLES PREPARED WITH SAME AND PREPARATION METHODS THEREOF | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-11-19 | — | — | WO | disclosed |
| CN-102713618-B | Protein Kinase Complexes and Inhibitors | CELGENE AVILOMICS RES INC | 2015-07-15 | — | — | CN | disclosed |
| WO-2012123966-A1 | PROCESS FOR THE PREPARATION OF 4 -SUBSTITUTED -1, 4-DIHYDROPYRIDINES | ARCH PHARMALABS LIMITED (IN) | 2012-09-20 | — | — | WO | disclosed |
| EP-1883630-A2 | METHODS OF SYNTHESIZING 6-ALKYLAMINOQUINOLINE DERIVATIVES | Wyeth (US) | 2008-02-06 | — | — | EP | disclosed |
| EP-1368315-B1 | METHOD FOR PREPARING AMLODIPINE | HANMI PHARM IND CO LTD (KR) | 2007-10-17 | — | — | EP | disclosed |
| EP-1089974-A1 | PROCESS TO PREPARE DIHYDROPYRIDINE AND DERIVATIVES THEREOF | Hoechst Celanese Corporation (US) | 2001-04-11 | — | — | EP | disclosed |
| US-5977369-A | Process to prepare dihydropyridine and derivatives thereof | NAPP TECHNOLOGIES, INC. (US) | 1999-11-02 | — | — | US | disclosed |
| US-5808084-A | Process for the preparation of 1,4-dihydropyridinedicarboxylic esters | PFIZER, INC. (US) | 1998-09-15 | — | — | US | disclosed |
| WO-1997024326-A1 | PROCESS TO PREPARE DIHYDROPYRIDINE AND DERIVATIVES THEREOF | HOECHST CELANESE CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |
| EP-0395182-A1 | Herbicidal compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-10-31 | — | — | EP | disclosed |
| US-4722931-A | MUSCLE RELAXANTS | LABORATORIOS DELAGRANGE (ES) | 1988-02-02 | — | — | US | disclosed |
| US-4038399-A | 1,4-DIHYDROPYRIDINE CARBOXYLIC ACID ESTERS USEFUL AS CORONARY VESSEL DILATORS AND ANTI-HYPERTENSIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-26 | — | — | US | disclosed |
| US-4031104-A | ANTIHYPERTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-21 | — | — | US | disclosed |
| US-3996234-A | CORONARY VESSEL DILATORS, HYPOTENSIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |
| US-3974275-A | 1,4-Dihydropyridine carboxylic acid esters useful as coronary vessel dilators and anti-hypertensives | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | disclosed |