⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909130 | 0.71 | — | — | |
| SCHEMBL2634020 | 0.70 | — | — | |
| SCHEMBL1515340 | 0.67 | — | — | |
| SCHEMBL188345 | 0.67 | — | — | |
| SCHEMBL17710343 | 0.67 | — | — | |
| SCHEMBL317518 | 0.67 | — | — | |
| SCHEMBL959376 | 0.67 | — | — | |
| SCHEMBL7525933 | 0.67 | — | — | |
| SCHEMBL488381 | 0.67 | — | — | |
| SCHEMBL335021 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2113 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121013-A1 | SULFONYL DERIVATIVES AS CCR6 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-06-13 | — | — | WO | claimed |
| EP-3634975-B1 | 17-OXIMES OF 15.BETA.-[3-PROPANAMIDO]-SUBSTITUTED ESTRA-1,3,5(10)-TRIEN-17-ONES FOR USE IN INHIBITION OF 17.BETA.-HYDROXYSTEROID DEHYDROGENASES | ORGANON R&D FINLAND LTD (FI) | 2024-02-28 | — | — | EP | claimed |
| US-20240025884-A1 | COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | DONG-A ST CO., LTD. (KR) | 2024-01-25 | — | — | US | claimed |
| WO-2024009215-A1 | NOVEL COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | DONG-A ST CO., LTD. (KR) | 2024-01-11 | — | — | WO | claimed |
| US-20230278996-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | MOLECURE S.A. (PL) | 2023-09-07 | — | — | US | claimed |
| US-20230096602-A1 | TETRAHYDROCYCLOPENTA[B]INDOLE COMPOUNDS FOR TREATMENT OF RENAL DISEASE | EIRGEN PHARMA LTD. (IE) | 2023-03-30 | — | — | US | claimed |
| CN-115720579-A | Antibacterial and antifungal pleuromutilin conjugates | 赛丹思科大学 | 2023-02-28 | — | — | CN | claimed |
| EP-4096660-A1 | TETRAHYDROCYCLOPENTA[B]INDOLE COMPOUNDS FOR THE TREATMENT OF RENAL DISEASE | EirGen Pharma Ltd. (IE) | 2022-12-07 | — | — | EP | claimed |
| CN-110945007-B | 15 beta- [ 3-propionylamino ] -substituted estra-1, 3,5 (10) -trien-17-one compounds and 17-oximes thereof for inhibiting 17 beta-hydroxysteroid dehydrogenases | 佛恩多制药有限公司 | 2022-11-18 | — | — | CN | claimed |
| US-11498926-B2 | Tricyclic heterocycles as BET protein inhibitors | INCYTE CORPORATION (US) | 2022-11-15 | — | — | US | claimed |
| EP-0005985-A1 | 3-Nitro pyrrole compounds, processes for preparing them and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-12-12 | — | — | EP | claimed |
| EP-0005984-A1 | Nitro compounds, processes for preparing them and compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-12-12 | — | — | EP | claimed |
| US-4159329-A | BLOCKING AGENTS, ANTAGONISTS, ANTIHISTAMINES | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-06-26 | — | — | US | claimed |
| US-4154834-A | HETEROCYCLIC-(THIO)ALKYLAMINO SUBSTITUTED-4-PYRIMIDONE OR -THIONES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-05-15 | — | — | US | claimed |
| EP-0000656-A1 | 4\"-Ureido-oleandomycin derivatives, process for their preparation and their use in pharmaceutical compositions | PFIZER INC. (US) | 1979-02-07 | — | — | EP | claimed |
| US-4120968-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1978-10-17 | — | — | US | claimed |
| US-4105770-A | HISTAMINE ANTIAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1978-08-08 | — | — | US | claimed |
| US-4098993-A | ANTIBACTERIAL | PFIZER INC. (US) | 1978-07-04 | — | — | US | claimed |
| US-4013659-A | CERTAIN N,N'-DISUBSTITUTED GUANIDINE COMPOUNDS AND THEIR USE | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-03-22 | — | — | US | claimed |
| US-3992535-A | ANTIINFLAMMATORY AGENTS, INHIBITORS OF PLATELET ADHESION AND AGGREGATION | BOEHRINGER INGELHEIM GMBH (DT) | 1976-11-16 | — | — | US | claimed |