Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947200 | 0.85 | FFAR1 (0.59) | FFAR1MTNR1AMTNR1BS1PR1S1PR3 | |
| SCHEMBL947719 | 0.83 | S1PR1 (0.70) | FFAR1S1PR1S1PR3PPARG | |
| Hydrochloric Acid SCHEMBL3541048 | 0.82 | S1PR1 (0.68) | FFAR1S1PR1S1PR3PPARG | |
| SCHEMBL948219 | 0.82 | S1PR1 (0.65) | FFAR1S1PR1S1PR3PPARG | |
| SCHEMBL948541 | 0.81 | S1PR1 (0.48) | FFAR1MTNR1AMTNR1BS1PR1S1PR3 | |
| SCHEMBL15890895 | 0.79 | S1PR1 (0.70) | FFAR1S1PR1S1PR3PPARG | |
| SCHEMBL15890904 | 0.78 | S1PR1 (0.71) | FFAR1S1PR1S1PR3PPARG | |
| Hydrochloric Acid SCHEMBL5722062 | 0.78 | S1PR1 (0.69) | FFAR1S1PR1S1PR3PPARG | |
| SCHEMBL1695082 | 0.78 | NR1H4 (0.58) | FFAR1 | |
| Hydrochloric Acid SCHEMBL948350 | 0.77 | S1PR1 (0.69) | FFAR1S1PR1S1PR3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8653305-B2 | Compound having S1P receptor binding potency and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-02-18 | — | — | US | claimed |
| US-8653305-B2 | Compound having S1P receptor binding potency and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-02-18 | — | — | US | disclosed |
| US-20080207584-A1 | Compound Having S1P Receptor Binding Potency and Use Thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207584-A1 | Compound Having S1P Receptor Binding Potency and Use Thereof | S1PR1, EDNRA, S1PR3 | FFAR1 57/4885MTNR1A 207/4885MTNR1B 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.