Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Anisole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.78 |
| ▸ | CES2 | O00748 | 3/20 | 0.64 |
| ▸ | CES1 | P23141 | 3/20 | 0.64 |
| ▸ | LTA4H | P09960 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | EDNRB | P24530 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anisole SCHEMBL5864971 | 1.00 | CA4 (0.78) | CA4CES2CES1LTA4HCA1 | |
| Anisole SCHEMBL5079940 | 0.97 | CA4 (0.74) | CA4CES2CES1LTA4HCA1 | |
| Anisole SCHEMBL3008918 | 0.92 | CA4 (0.74) | CA4CES2CES1LTA4HCA1 | |
| Anisole SCHEMBL28307620 | 0.92 | CA4 (0.74) | CA4CES2CES1LTA4HCA1 | |
| Anisole SCHEMBL30068922 | 0.92 | CA4 (0.74) | CA4CES2CES1LTA4HCA1 | |
| Anisole SCHEMBL5696157 | 0.92 | CA4 (0.74) | CA4CES2CES1LTA4HCA1 | |
| Anisole SCHEMBL29140274 | 0.92 | CA4 (0.74) | CA4CES2CES1LTA4HCA1 | |
| Anisole SCHEMBL29169488 | 0.91 | CA4 (0.93) | CA4CES2CES1LTA4HCA1 | |
| Anisole SCHEMBL9460563 | 0.90 | CA4 (0.70) | CA4CES2CES1LTA4HCA1 | |
| Anisole SCHEMBL9696388 | 0.90 | CA4 (0.70) | CA4CES2CES1LTA4HCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112225647-A | Method for synthesizing 5-bromo-2-methoxyphenol | 河南中医药大学 | 2021-01-15 | — | — | CN | claimed |
| CN-112225647-A | Method for synthesizing 5-bromo-2-methoxyphenol | 河南中医药大学 | 2021-01-15 | — | — | CN | disclosed |
| WO-2008034265-A1 | PROCESS FOR THE PREPARATION OF ALKYLENE CARBONATES | MCGILL UNIVERSITY (CA) | 2008-03-27 | — | — | WO | disclosed |
| EP-0468921-B2 | Aqueous dispersions of slightly soluble UV absorbing agents | CIBA GEIGY AG (CH) | 1998-07-22 | — | — | EP | disclosed |
| EP-0523006-B1 | Process for printing and photochemically stabilizing polyester fibre materials | CIBA GEIGY AG (CH) | 1995-11-29 | — | — | EP | disclosed |
| EP-0474595-B1 | Aqueous dispersion of low-solubility UV-absorbers | CIBA GEIGY AG (CH) | 1995-09-27 | — | — | EP | disclosed |
| EP-0490819-B1 | Aqueous dispersion of slightly water soluble U.V. absorbers | CIBA GEIGY AG (CH) | 1995-09-13 | — | — | EP | disclosed |
| EP-0345219-B1 | Aqueous dispersions of 2-(2'-hydroxyphenyl) benzotriazoles | CIBA GEIGY AG (CH) | 1994-02-02 | — | — | EP | disclosed |
| EP-0523006-A1 | Process for printing and photochemically stabilizing polyester fibre materials | CIBA-GEIGY AG (CH) | 1993-01-13 | — | — | EP | disclosed |
| EP-0490819-A1 | Aqueous dispersion of slightly water soluble U.V. absorbers | CIBA-GEIGY AG (CH) | 1992-06-17 | — | — | EP | disclosed |
| EP-0474595-A1 | Aqueous dispersion of low-solubility UV-absorbers | CIBA-GEIGY AG (CH) | 1992-03-11 | — | — | EP | disclosed |
| EP-0468921-A1 | Aqueous dispersions of slightly soluble UV absorbing agents | CIBA-GEIGY AG (CH) | 1992-01-29 | — | — | EP | disclosed |
| EP-0357545-A2 | Cationic compounds, their preparation and their use in the photochemical stabilisation of basic dyeable polyamide polyacrylonitrile and polyester fibres | CIBA-GEIGY AG (CH) | 1990-03-07 | — | — | EP | disclosed |
| EP-0354174-A1 | Stable aqueous composition for modifying light fastness | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |
| EP-0345219-A1 | Aqueous dispersions of 2-(2'-hydroxyphenyl) benzotriazoles | CIBA-GEIGY AG (CH) | 1989-12-06 | — | — | EP | disclosed |
| EP-0064030-B1 | DYEING AUXILIARY MIXTURE AND ITS USE IN DYEING SYNTHETIC FIBROUS MATERIALS | CIBA-GEIGY AG (CH) | 1985-01-16 | — | — | EP | disclosed |
| EP-0064030-A1 | Dyeing auxiliary mixture and its use in dyeing synthetic fibrous materials | CIBA-GEIGY AG (CH) | 1982-11-03 | — | — | EP | disclosed |