Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.55 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3614411 | 0.92 | KMT2A (0.74) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL27630054 | 0.90 | KMT2A (0.72) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL27650016 | 0.86 | KMT2A (0.69) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL27650147 | 0.85 | KMT2A (1.00) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL27630315 | 0.84 | KMT2A (0.69) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL27650029 | 0.84 | KMT2A (0.66) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL27650005 | 0.84 | KMT2A (0.77) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL3609060 | 0.82 | KMT2A (0.73) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL28756782 | 0.82 | KMT2A (0.72) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL4964870 | 0.82 | KMT2A (0.49) | KMT2AMEN1POLBALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888544-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | Takeda San Diego, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006066109-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-06-22 | — | — | WO | disclosed |