Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 1.00 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.71 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1614514 | 1.00 | DPP4 (1.00) | DPP4DPP7DPP8 | |
| SCHEMBL6596978 | 0.88 | DPP4 (1.00) | DPP4DPP7DPP8 | |
| SCHEMBL464944 | 0.86 | DPP4 (0.76) | DPP4DPP7DPP8 | |
| SCHEMBL666219 | 0.85 | DPP4 (0.74) | DPP4DPP7DPP8 | |
| SCHEMBL4594039 | 0.85 | DPP4 (0.74) | DPP4DPP7DPP8 | |
| SCHEMBL666255 | 0.84 | DPP4 (0.72) | DPP4DPP7DPP8 | |
| Hydrochloric Acid SCHEMBL6697642 | 0.84 | DPP4 (0.72) | DPP4DPP7DPP8 | |
| SCHEMBL4594376 | 0.84 | DPP4 (0.72) | DPP4DPP7DPP8 | |
| SCHEMBL5077374 | 0.84 | DPP4 (0.75) | DPP4DPP7DPP8 | |
| SCHEMBL6702155 | 0.84 | DPP4 (0.75) | DPP4DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898904-A2 | MODIFIED RELEASE 1-[(3-HYDROXY-ADAMANT-1-YLAMINO)-ACETYL]-PYRROLIDINE-2(S)-CARBONITRILE FORMULATION | Novartis AG (CH) | 2008-03-19 | — | — | EP | disclosed |
| WO-2006135723-A2 | MODIFIED RELEASE 1-[(3-HYDROXY-ADAMANT-1-YLAMINO)-ACETYL]-PYRROLIDINE-2(S)-CARBONITRILE FORMULATION | NOVARTIS AG (CH) | 2006-12-21 | — | — | WO | disclosed |