Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 17/20 | 0.76 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | TK1 | P04183 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17186521 | 0.99 | PNP (0.74) | PNPADORA2AXDHTK1 | |
| SCHEMBL18249 | 0.86 | PNP (1.00) | PNPXDHTK1 | |
| SCHEMBL1980959 | 0.85 | PNP (0.97) | PNPXDHTK1 | |
| SCHEMBL27868175 | 0.83 | PNP (0.76) | PNPTK1 | |
| SCHEMBL17186515 | 0.83 | PNP (0.68) | PNPTK1 | |
| SCHEMBL8145519 | 0.83 | PNP (0.72) | PNPXDHTK1 | |
| SCHEMBL1262622 | 0.83 | PNP (0.79) | PNPTK1 | |
| SCHEMBL3308559 | 0.83 | PNP (0.79) | PNPXDHTK1 | |
| SCHEMBL3304421 | 0.82 | PNP (0.74) | PNPTK1 | |
| SCHEMBL20970000 | 0.82 | PNP (0.74) | PNPADORA2AXDHTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4054057-B2 | — | — | 2008-02-27 | — | — | JP | claimed |
| EP-0702683-B1 | 06-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER REC TECH LTD (GB) | 2003-09-17 | — | — | EP | claimed |
| CN-1048493-C | 06-substituted guanine derivatives, a process for their prepn. and their use | CANCER RES CAMPAIGN TECH (GB) | 2000-01-19 | — | — | CN | claimed |
| CN-1145622-A | O 6Substituted guanine derivatives, process for their preparation and their use | CANCER RES CAMPAIGN TECH (GB) | 1997-03-19 | — | — | CN | claimed |
| WO-1994029312-A1 | O6-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1994-12-22 | — | — | WO | claimed |
| JP-7278145-A | — | — | None | — | — | JP | disclosed |
| EP-3131877-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | Immunomet Therapeutics Inc. (US) | 2017-02-22 | — | — | EP | disclosed |
| WO-2015160220-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | HANALL BIOPHARMA CO., LTD. (KR) | 2015-10-22 | — | — | WO | disclosed |
| EP-0702683-B8 | 06-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER REC TECH LTD (GB) | 2004-09-08 | — | — | EP | disclosed |
| CN-1048493-C | 06-substituted guanine derivatives, a process for their prepn. and their use | CANCER RES CAMPAIGN TECH (GB) | 2000-01-19 | — | — | CN | disclosed |
| CN-1145622-A | O 6Substituted guanine derivatives, process for their preparation and their use | CANCER RES CAMPAIGN TECH (GB) | 1997-03-19 | — | — | CN | disclosed |
| EP-0702683-A1 | 06-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-03-27 | — | — | EP | disclosed |
| JP-H07278145-A | GUANINE DERIVATIVE | TOAGOSEI CO LTD | 1995-10-24 | — | — | JP | disclosed |
| WO-1994029312-A1 | O6-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |