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Sugi Predict / Compounds / 2,4-Dichlorophenoxyacetic Acid

2,4-Dichlorophenoxyacetic Acid

2,4-Dichlorophenoxyacetic Acid

SCHEMBL4967210

O=C(O)COc1ccc(Cl)cc1Cl.c1ccc2ncccc2c1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.68
▸ TSHR P16473 1/20 0.61
▸ NPC1 O15118 3/20 0.55
▸ RAB9A P51151 3/20 0.55
▸ MITF O75030 1/20 0.55
▸ TP53 P04637 1/20 0.55
▸ PKM P14618 1/20 0.55
▸ HPGD P15428 1/20 0.55
▸ XBP1 P17861 1/20 0.55
▸ PTGDR2 Q9Y5Y4 7/20 0.53
▸ GAA P10253 1/20 0.50
▸ NFKB1 P19838 1/20 0.50
▸ NFKB2 Q00653 1/20 0.50
▸ RELA Q04206 1/20 0.50
▸ THRB P10828 1/20 0.49
▸ KDM4E B2RXH2 1/20 0.49
▸ ALDH1A1 P00352 1/20 0.49
▸ MAPT P10636 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,4-Dichlorophenoxyacetic Acid SCHEMBL28380449 0.87 TDP1 (0.84) TDP1TSHRNPC1RAB9AMITF
2,4-Dichlorophenoxyacetic Acid SCHEMBL31108925 0.82 TDP1 (1.00) TDP1TSHRHPGDPTGDR2GAA
2,4-Dichlorophenoxyacetic Acid SCHEMBL11716042 0.82 TDP1 (1.00) TDP1TSHRHPGDPTGDR2GAA
2,4-Dichlorophenoxyacetic Acid SCHEMBL27783 0.82 TDP1 (1.00) TDP1TSHRHPGDPTGDR2GAA
2,4-Dichlorophenoxyacetic Acid SCHEMBL226803 0.82 TDP1 (1.00) TDP1TSHRHPGDPTGDR2GAA
2,4-Dichlorophenoxyacetic Acid SCHEMBL1648664 0.82 TDP1 (0.75) TDP1TSHRNPC1RAB9AMITF
2,4-Dichlorophenoxyacetic Acid SCHEMBL30969691 0.81 TDP1 (0.84) TDP1TSHRPTGDR2MAPT
2,4-Dichlorophenoxyacetic Acid SCHEMBL9590404 0.81 TDP1 (0.96) TDP1TSHRHPGDPTGDR2GAA
2,4-Dichlorophenoxyacetic Acid SCHEMBL4586671 0.81 TDP1 (0.96) TDP1TSHRNPC1RAB9AHPGD
2,4-Dichlorophenoxyacetic Acid SCHEMBL7618485 0.81 TDP1 (0.96) TDP1TSHRHPGDPTGDR2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1954252-A2 NANOPARTICLES FOR USE IN IMMUNOGENIC COMPOSITIONS Novartis AG (CH) 2008-08-13 — — EP disclosed
WO-2008051245-A2 NANOPARTICLES FOR USE IN IMMUNOGENIC COMPOSITIONS NOVARTIS AG (CH) 2008-05-02 — — WO disclosed