Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134919 | 0.97 | TSHR (0.39) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Ethylene Glycol SCHEMBL28396571 | 0.94 | TSHR (0.37) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL28928131 | 0.87 | — | — | |
| SCHEMBL6468155 | 0.84 | TSHR (0.33) | TSHRMAPK1ALDH1A1 | |
| SCHEMBL10308656 | 0.84 | — | — | |
| SCHEMBL3478104 | 0.84 | — | — | |
| SCHEMBL16007816 | 0.80 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL28496778 | 0.80 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL28500245 | 0.80 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL13909030 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758252-B1 | TIN-117m-CONTAINING RADIOTHERAPEUTIC AGENTS | BROOKHAVEN SCIENCE ASS LLC (US) | 2008-09-03 | — | — | EP | claimed |
| EP-0758252-A1 | TIN-117m-CONTAINING RADIOTHERAPEUTIC AGENTS | ASSOCIATED UNIVERSITIES, INC. (US) | 1997-02-19 | — | — | EP | claimed |
| WO-1995029706-A1 | TIN-117m-CONTAINING RADIOTHERAPEUTIC AGENTS | ASSOCIATED UNIVERSITIES, INC. (US) | 1995-11-09 | — | — | WO | claimed |