Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31305170 | 1.00 | GAA (0.48) | GAAAKR1B1TSHRALDH1A1ALOX15 | |
| SCHEMBL31085452 | 1.00 | GAA (0.48) | GAAAKR1B1TSHRALDH1A1ALOX15 | |
| SCHEMBL4972047 | 1.00 | GAA (0.48) | GAAAKR1B1TSHRALDH1A1ALOX15 | |
| SCHEMBL2446612 | 0.95 | GAA (0.52) | GAAAKR1B1TSHRALDH1A1ALOX15 | |
| SCHEMBL164713 | 0.95 | — | — | |
| SCHEMBL29786950 | 0.93 | TSHR (0.56) | AKR1B1TSHRALDH1A1ALOX15GPR84 | |
| SCHEMBL11702957 | 0.93 | GAA (0.50) | GAAAKR1B1TSHRALDH1A1ALOX15 | |
| Ammonia Solution, Strong SCHEMBL4280114 | 0.93 | GAA (0.50) | GAAAKR1B1TSHRALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL6618473 | 0.93 | GAA (0.50) | GAAAKR1B1TSHRALDH1A1ALOX15 | |
| SCHEMBL3177441 | 0.91 | TSHR (0.54) | TSHRALDH1A1ALOX15GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957518-A1 | NEW CYCLIC PEPTIDE COMPOUNDS | Astellas Pharma Inc. (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007049803-A1 | NEW CYCLIC PEPTIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2007-05-03 | — | — | WO | disclosed |