Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 13/20 | 0.38 |
| ▸ | PDE4A | P27815 | 6/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 6/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967985 | 1.00 | PDE4D (0.38) | PDE4DPDE4APDE4BPDE4CSLC5A2 | |
| SCHEMBL14116528 | 1.00 | PDE4D (0.38) | PDE4DPDE4APDE4BPDE4CSLC5A2 | |
| SCHEMBL4966210 | 0.86 | KMT2A (0.41) | SLC5A2SLC5A1 | |
| SCHEMBL4966844 | 0.82 | PDE4D (0.45) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL4967088 | 0.82 | PDE4D (0.45) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL4967734 | 0.80 | PDE4D (0.38) | PDE4DPDE4APDE4BPDE4CSLC5A2 | |
| SCHEMBL4968649 | 0.80 | PDE4D (0.38) | PDE4DPDE4APDE4BPDE4CSLC5A2 | |
| SCHEMBL4967723 | 0.80 | PDE4D (0.38) | PDE4DPDE4APDE4BPDE4CSLC5A2 | |
| SCHEMBL4966730 | 0.78 | IKBKE (0.36) | PDE4DPDE4APDE4BPDE4CSLC5A2 | |
| SCHEMBL4966718 | 0.78 | IKBKE (0.36) | PDE4DPDE4APDE4BPDE4CSLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008101938-A1 | GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZONITRILE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-28 | — | — | WO | disclosed |
| WO-2008101938-A1 | GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZONITRILE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-28 | — | — | WO | disclosed |