⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951102 | 0.65 | — | — | |
| SCHEMBL11810865 | 0.63 | ABCG2 (0.34) | — | |
| SCHEMBL18805998 | 0.57 | — | — | |
| SCHEMBL2503096 | 0.55 | — | — | |
| SCHEMBL482353 | 0.54 | — | — | |
| SCHEMBL18301324 | 0.52 | — | — | |
| SCHEMBL2691142 | 0.51 | — | — | |
| SCHEMBL2813723 | 0.51 | — | — | |
| SCHEMBL4872377 | 0.46 | DYRK1A (0.32) | — | |
| Naphthalene SCHEMBL1272176 | 0.45 | IDO1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024141554-A1 | COMPOUNDS AFFECTING KRAS | UNIVERSITAT DE BARCELONA (ES) | 2024-07-04 | — | — | WO | claimed |
| EP-4393908-A1 | BIS-PYRAZOLYL-METHANE COMPOUNDS AFFECTING KRAS | Universitat de Barcelona (ES) | 2024-07-03 | — | — | EP | claimed |
| WO-2024099393-A1 | ARYL-CONTAINING AMINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2024-05-16 | — | — | WO | claimed |
| CN-116041198-A | Method for synthesizing amide derivative by vanadium catalysis | 陕西师范大学 | 2023-05-02 | — | — | CN | claimed |
| CN-112047797-B | Method for preparing alpha-alkyl substituted ketone compound | 赣南医学院 | 2023-04-07 | — | — | CN | claimed |
| CN-114853795-A | Arylboron compound of conjugated olefin and preparation method and application thereof | 南京工业大学 | 2022-08-05 | — | — | CN | claimed |
| CN-113683493-B | Electron-rich conjugated diene compound, preparation method and application | 四川大学 | 2022-06-10 | — | — | CN | claimed |
| EP-3324974-B1 | COMPOUNDS, COMPOSITIONS, METHODS FOR TREATING DISEASES, AND METHODS FOR PREPARING COMPOUNDS | UNIV LOUISVILLE RES FOUND INC (US) | 2022-06-08 | — | — | EP | claimed |
| CN-111196922-B | Application of pH-sensitive beta-carboline derivative fluorescent probe in tumor fluorescence imaging | 南通大学 | 2022-05-06 | — | — | CN | claimed |
| US-11312690-B2 | Compounds, compositions, methods for treating diseases, and methods for preparing compounds | UNIVERSITY OF LOUSVILLE RESEARCH FOUNDATION, INC. (US) | 2022-04-26 | — | — | US | claimed |
| EP-1216249-B1 | THIENOISOXAZOLE PHENOXY UNSUBSTITUTED ETHYL AND PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMA INC (US) | 2003-11-19 | — | — | EP | claimed |
| EP-1216250-B1 | THIENOISOXAZOLYL AND THIENYLPYRRAZOLYL PHENOXY SUBSTITUTED PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMA INC (US) | 2003-11-19 | — | — | EP | claimed |
| CN-1120825-C | Acylation method of aromatic compound | RHONE POULENC CHIMIE (FR) | 2003-09-10 | — | — | CN | claimed |
| EP-1216244-B1 | Benzisoxazolyl-, pyridoisoxazolyl- and benzthienyl-phenoxy derivatives useful as D4 antagonists | AVENTIS PHARMA INC (US) | 2003-08-13 | — | — | EP | claimed |
| US-5998414-A | PSYCHOLOGICAL DISORDERS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-07 | — | — | US | claimed |
| CN-1222131-A | Acylation method for aromatic compound | RHONE POULENC CHIMIE (FR) | 1999-07-07 | — | — | CN | claimed |
| EP-0796270-A2 | PEPTIDE COMPOUNDS FOR PREVENTION AND/OR TREATMENT OF NO-MEDIATED DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-24 | — | — | EP | claimed |
| WO-1996016981-A2 | PEPTIDE COMPOUNDS FOR PREVENTION AND/OR TREATMENT OF NO-MEDIATED DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-06 | — | — | WO | claimed |
| US-4140681-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1979-02-20 | — | — | US | claimed |
| US-4125604-A | PEPTIDES, ANTITHROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1978-11-14 | — | — | US | claimed |