SCHEMBL4968366

SCHEMBL4968366

CC(NC(=O)CN)C(=O)NC(C(=O)O)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.43
MME P08473 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
PLA2G2A P14555 1/20 0.38
PLA2G5 P39877 1/20 0.38
ALDH1A1 P00352 4/20 0.38
POLB P06746 1/20 0.38
CTSC P53634 1/20 0.38
SDCBP O00560 2/20 0.37
SDC2 P34741 2/20 0.37
FNTA P49354 1/20 0.36
FNTB P49356 1/20 0.36
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29531660 1.00 NPSR1 (0.43) NPSR1MMESMN1; SMN2PLA2G2APLA2G5
SCHEMBL4968369 1.00 NPSR1 (0.43) NPSR1MMESMN1; SMN2PLA2G2APLA2G5
SCHEMBL30997444 0.98 NPSR1 (0.42) NPSR1MMESMN1; SMN2PLA2G2APLA2G5
SCHEMBL29839283 0.95 NPSR1 (0.40) NPSR1MMESMN1; SMN2PLA2G2APLA2G5
SCHEMBL31265320 0.92 NPSR1 (0.38) NPSR1MMESMN1; SMN2PLA2G2APLA2G5
Trifluoroacetic Acid SCHEMBL4392857 0.91 NPSR1 (0.38) NPSR1MMESMN1; SMN2PLA2G2APLA2G5
SCHEMBL31631407 0.88 MME (0.39) MMESMN1; SMN2ALDH1A1CTSC
SCHEMBL29380611 0.87 NPSR1 (0.47) NPSR1MMESMN1; SMN2PLA2G2APLA2G5
SCHEMBL232334 0.87 NPSR1 (0.53) NPSR1SMN1; SMN2PLA2G2APLA2G5ALDH1A1
SCHEMBL2081229 0.87 NPSR1 (0.53) NPSR1SMN1; SMN2PLA2G2APLA2G5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP claimed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US claimed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP claimed
EP-1959919-A1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2008-08-27 EP disclosed
WO-2007068401-A1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2007-06-21 WO disclosed
US-6679761-B1 CHEMICAL MECHANICAL POLISHING; ABRASIVE GRAINS, A PEPTIDE, AN OXIDIZER SUSPENDED IN AQUEOUS MEDIUM SEIMI CHEMICAL CO., LTD. (JP) 2004-01-20 US disclosed
EP-1235261-A1 POLISHING COMPOUND FOR SEMICONDUCTOR CONTAINING PEPTIDE Seimi Chemical Co., Ltd. (JP) 2002-08-28 EP disclosed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP disclosed