Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4966153 | 0.89 | CNR2 (0.58) | CNR2KCNH2CNR1 | |
| SCHEMBL5438189 | 0.86 | CNR2 (0.49) | CNR2KCNH2CNR1 | |
| SCHEMBL14523981 | 0.84 | CNR2 (0.51) | CNR2CNR1 | |
| SCHEMBL4967057 | 0.83 | CNR2 (0.49) | CNR2CNR1 | |
| SCHEMBL4968859 | 0.81 | CNR2 (0.61) | CNR2KCNH2CNR1 | |
| SCHEMBL4967056 | 0.80 | CNR2 (0.62) | CNR2KCNH2CNR1 | |
| SCHEMBL4969171 | 0.79 | CNR2 (0.61) | CNR2KCNH2CNR1 | |
| SCHEMBL4967717 | 0.79 | CNR2 (0.61) | CNR2KCNH2CNR1 | |
| SCHEMBL4974878 | 0.79 | CNR2 (0.61) | CNR2KCNH2CNR1 | |
| SCHEMBL4965538 | 0.78 | CNR2 (0.61) | CNR2KCNH2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670770-B1 | BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEROF AND USES THEREOF | ASTRAZENECA AB (SE) | 2008-08-20 | — | — | EP | disclosed |