SCHEMBL4968515

SCHEMBL4968515

CN(c1ccc2c(c1)nc(C(F)F)n2CC1CCOCC1)S(=O)(=O)c1ccc(NC(=O)CO)cc1

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 18/20 0.47
CNR1 P21554 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4966343 0.92 CNR2 (0.49) CNR2CNR1L3MBTL1
SCHEMBL4970023 0.90 CNR2 (0.47) CNR2CNR1
SCHEMBL4966140 0.88 CNR2 (0.53) CNR2CNR1
SCHEMBL4967409 0.88 CNR2 (0.54) CNR2CNR1
SCHEMBL4967032 0.88 CNR2 (0.62) CNR2CNR1
SCHEMBL4967801 0.85 CNR2 (0.53) CNR2CNR1
SCHEMBL4965890 0.81 CNR2 (0.51) CNR2CNR1
SCHEMBL4976175 0.81 CNR2 (0.63) CNR2CNR1
SCHEMBL4966759 0.81 CNR2 (0.60) CNR2CNR1
SCHEMBL4967055 0.81 CNR2 (0.61) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670770-B1 BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEROF AND USES THEREOF ASTRAZENECA AB (SE) 2008-08-20 EP claimed