Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.58 |
| ▸ | USP5 | P45974 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2422935 | 0.95 | MAPK9 (0.63) | MEN1KMT2AMAPK9MAPK10USP5 | |
| SCHEMBL2423811 | 0.92 | MEN1 (0.68) | MEN1KMT2AMAPK9MAPK10USP5 | |
| SCHEMBL2426036 | 0.90 | MAPK9 (0.64) | MEN1KMT2AMAPK9MAPK10USP5 | |
| SCHEMBL7443885 | 0.85 | MAPK9 (0.54) | MEN1KMT2AMAPK9MAPK10USP5 | |
| SCHEMBL2423768 | 0.85 | MAPK9 (0.60) | MEN1KMT2AMAPK9MAPK10TP53 | |
| SCHEMBL4964842 | 0.84 | MEN1 (0.59) | MEN1KMT2AMAPK9MAPK10TP53 | |
| SCHEMBL2422723 | 0.83 | MAPK9 (0.62) | MEN1KMT2AMAPK9MAPK10USP5 | |
| SCHEMBL2419385 | 0.83 | MAPK9 (0.54) | MEN1KMT2AMAPK9MAPK10USP5 | |
| SCHEMBL2420297 | 0.81 | MEN1 (0.61) | MEN1KMT2AMAPK9MAPK10USP5 | |
| SCHEMBL6430927 | 0.81 | MAPK9 (0.62) | MEN1KMT2AMAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904181-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011762-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | disclosed |