Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | BCL2 | P10415 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | USP5 | P45974 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2423150 | 0.94 | MAPK9 (0.58) | MAPK9MAPK10MEN1KMT2AMAPK1 | |
| SCHEMBL2425799 | 0.93 | KMT2A (0.52) | MAPK9MAPK10MEN1KMT2ATDP1 | |
| SCHEMBL2421313 | 0.93 | MAPK9 (0.55) | MAPK9MAPK10MEN1KMT2ATDP1 | |
| SCHEMBL4190246 | 0.91 | MAPK9 (0.49) | MAPK9MAPK10MEN1KMT2AMAPK1 | |
| SCHEMBL2426626 | 0.88 | MEN1 (0.56) | MAPK9MAPK10MEN1KMT2ATDP1 | |
| SCHEMBL1518918 | 0.85 | MAPK9 (0.62) | MAPK9MAPK10MEN1KMT2ATDP1 | |
| SCHEMBL2421220 | 0.85 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2425463 | 0.85 | MEN1 (0.50) | MAPK9MAPK10MEN1KMT2AMAPK1 | |
| SCHEMBL2423026 | 0.85 | MAPK9 (0.51) | MAPK9MAPK10MEN1KMT2AL3MBTL1 | |
| SCHEMBL2420301 | 0.85 | MAPK9 (0.51) | MAPK9MAPK10MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976835-A2 | HISTONE DEACETYLASE INHIBITORS | Takeda San Diego, Inc. (US) | 2008-10-08 | — | — | EP | claimed |
| WO-2007084390-A2 | HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2007-07-26 | — | — | WO | claimed |
| EP-1904181-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011762-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | disclosed |