Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.45 |
| ▸ | KMT5B | Q4FZB7 | 2/20 | 0.44 |
| ▸ | KMT5C | Q86Y97 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29862882 | 1.00 | MKNK1 (0.48) | MKNK1MKNK2CHEK2CHEK1HTR1A | |
| SCHEMBL900098 | 1.00 | MKNK1 (0.48) | MKNK1MKNK2CHEK2CHEK1HTR1A | |
| Hydrochloric Acid SCHEMBL29862725 | 0.99 | MKNK1 (0.47) | MKNK1MKNK2CHEK2CHEK1HTR1A | |
| Hydrochloric Acid SCHEMBL29862477 | 0.99 | MKNK1 (0.47) | MKNK1MKNK2CHEK2CHEK1HTR1A | |
| Hydrochloric Acid SCHEMBL29862720 | 0.99 | MKNK1 (0.47) | MKNK1MKNK2CHEK2CHEK1HTR1A | |
| Hydrochloric Acid SCHEMBL23360261 | 0.99 | MKNK1 (0.47) | MKNK1MKNK2CHEK2CHEK1HTR1A | |
| Hydrochloric Acid SCHEMBL23360250 | 0.99 | MKNK1 (0.47) | MKNK1MKNK2CHEK2CHEK1HTR1A | |
| Hydrochloric Acid SCHEMBL23360251 | 0.99 | MKNK1 (0.47) | MKNK1MKNK2CHEK2CHEK1HTR1A | |
| SCHEMBL12634152 | 0.91 | KMT5B (0.49) | MKNK1HTR1AADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL23360249 | 0.90 | KMT5B (0.48) | MKNK1HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |
| EP-1899319-A2 | AMINOQUINOLINE AND AMINOQUINAZOLINE KINASE MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2006135649-A2 | AMINOQUINOLINE AND AMINOQUINAZOLINE KINASE MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-12-21 | — | — | WO | disclosed |