Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 8/20 | 0.56 |
| ▸ | CCR3 | P51677 | 8/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.56 |
| ▸ | AR | P10275 | 11/20 | 0.45 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967137 | 0.93 | HRH1 (0.66) | HRH1CCR3KCNH2AR | |
| SCHEMBL4967165 | 0.91 | HRH1 (0.69) | HRH1CCR3KCNH2AR | |
| SCHEMBL4967140 | 0.90 | HRH1 (0.69) | HRH1CCR3KCNH2 | |
| SCHEMBL4967810 | 0.90 | HRH1 (0.46) | HRH1CCR3KCNH2AR | |
| SCHEMBL4968661 | 0.84 | HRH1 (0.53) | HRH1CCR3KCNH2AR | |
| SCHEMBL4967374 | 0.84 | HRH1 (0.80) | HRH1CCR3KCNH2 | |
| SCHEMBL4969650 | 0.83 | HRH1 (0.53) | HRH1CCR3KCNH2AR | |
| SCHEMBL4968313 | 0.83 | HRH1 (0.81) | HRH1CCR3KCNH2 | |
| SCHEMBL4967181 | 0.82 | HRH1 (0.54) | HRH1CCR3KCNH2AR | |
| SCHEMBL4966034 | 0.81 | HRH1 (0.54) | HRH1CCR3KCNH2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625114-B1 | Piperidine derivatives for the the treatment of chemokine or H1 mediated diseases | ASTRAZENECA AB (SE) | 2008-08-27 | — | — | EP | disclosed |