SCHEMBL4969558

SCHEMBL4969558

CCCCCC(=O)N(C)Cc1cccc(-c2cc(CC)c(CCC(=O)O)c(CC)c2)c1

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 13/20 0.48
FOLH1 Q04609 1/20 0.43
KMT2A Q03164 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
FFAR1 O14842 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4968474 0.90 AOC3 (0.44) AOC3
SCHEMBL4969992 0.89 AOC3 (0.48) AOC3FOLH1KMT2ANPC1RAB9A
SCHEMBL4968711 0.88 AOC3 (0.46) AOC3FOLH1KMT2ANPC1RAB9A
SCHEMBL4971505 0.87 AOC3 (0.46) AOC3FOLH1KMT2AFFAR1
SCHEMBL4970598 0.85 AOC3 (0.53) AOC3KMT2AFFAR1
SCHEMBL4968583 0.85 AOC3 (0.46) AOC3FOLH1NPC1RAB9A
SCHEMBL4968795 0.83 AOC3 (0.46) AOC3FOLH1KMT2A
SCHEMBL4970036 0.83 AOC3 (0.44) AOC3FOLH1KMT2A
SCHEMBL4969484 0.82 FFAR1 (0.48) AOC3FOLH1FFAR1
SCHEMBL4969521 0.79 PTGER4 (0.47) AOC3FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1781274-B1 NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE RECEPTORS OF PPAR TYPE AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS GALDERMA RES & DEV (FR) 2008-11-05 EP claimed