Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2425242 | 0.92 | MEN1 (0.45) | MEN1KMT2ACYP1A2CYP3A4MAPK9 | |
| SCHEMBL2420394 | 0.91 | CYP1A2 (0.46) | MEN1KMT2ACYP1A2CYP3A4MAPK9 | |
| SCHEMBL3479856 | 0.86 | MEN1 (0.45) | MEN1KMT2ACYP1A2CYP3A4MAPK9 | |
| SCHEMBL4969547 | 0.86 | MEN1 (0.40) | MEN1KMT2AMAPK9MAPK10ALDH1A1 | |
| SCHEMBL2426717 | 0.84 | CYP1A2 (0.45) | MEN1KMT2ACYP1A2CYP3A4MAPK9 | |
| SCHEMBL4197520 | 0.84 | MEN1 (0.38) | MEN1KMT2ACYP1A2CYP3A4MAPK9 | |
| SCHEMBL2423715 | 0.84 | MEN1 (0.47) | MEN1KMT2AMAPK9MAPK10ALDH1A1 | |
| SCHEMBL6431835 | 0.83 | MEN1 (0.55) | MEN1KMT2AMAPK9MAPK10ALDH1A1 | |
| SCHEMBL2423145 | 0.83 | MEN1 (0.46) | MEN1KMT2ACYP1A2CYP3A4MAPK9 | |
| SCHEMBL2428331 | 0.83 | KMT2A (0.51) | MEN1KMT2ACYP1A2CYP3A4MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904181-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011762-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | disclosed |