Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.64 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2422218 | 0.89 | MAPK9 (0.80) | MAPK9MAPK10L3MBTL1MEN1KMT2A | |
| SCHEMBL2424820 | 0.88 | MEN1 (0.50) | MAPK9MAPK10L3MBTL1MEN1KMT2A | |
| SCHEMBL4204314 | 0.86 | MAPK9 (0.73) | MAPK9MAPK10L3MBTL1MEN1KMT2A | |
| SCHEMBL2419679 | 0.83 | MAPK9 (0.72) | MAPK9MAPK10MEN1KMT2ALMNA | |
| SCHEMBL2428274 | 0.82 | MEN1 (0.50) | MAPK9MAPK10L3MBTL1MEN1KMT2A | |
| SCHEMBL1518774 | 0.79 | MAPK9 (1.00) | MAPK9MAPK10L3MBTL1MEN1KMT2A | |
| SCHEMBL1518770 | 0.78 | MAPK9 (0.55) | MAPK9MAPK10L3MBTL1MEN1KMT2A | |
| SCHEMBL4192938 | 0.78 | KMT2A (0.41) | MAPK9MAPK10L3MBTL1MEN1KMT2A | |
| SCHEMBL2425364 | 0.78 | MAPK9 (0.80) | MAPK9MAPK10L3MBTL1MEN1KMT2A | |
| SCHEMBL7436716 | 0.78 | MAPK9 (0.58) | MAPK9MAPK10L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904181-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011762-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | disclosed |