Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.47 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | CCR2 | P41597 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanol SCHEMBL27629045 | 1.00 | OR51E2 (0.54) | OR51E2CRBNFKBP5LMNAALDH1A1 | |
| 1-Pentanol SCHEMBL28143808 | 0.98 | OR51E2 (0.56) | OR51E2CRBNFKBP5LMNAALDH1A1 | |
| 2-Pyrrolidone SCHEMBL28259292 | 0.93 | OR51E2 (0.58) | OR51E2CRBNFKBP5LMNAALDH1A1 | |
| Oleyl Alcohol SCHEMBL8908970 | 0.91 | OR51E2 (0.44) | OR51E2LMNAHSD17B10MEN1KMT2A | |
| 1,6-Hexanediol SCHEMBL7071741 | 0.91 | OR51E2 (0.65) | OR51E2CRBNFKBP5LMNAKMT2A | |
| Hexane SCHEMBL6861569 | 0.89 | OR51E2 (0.68) | OR51E2CRBNFKBP5LMNAALOX5 | |
| 2-Pyrrolidone SCHEMBL28327039 | 0.87 | OR51E2 (0.65) | OR51E2CRBNFKBP5LMNAALDH1A1 | |
| Dodecane SCHEMBL28204455 | 0.85 | CRBN (0.67) | OR51E2CRBNFKBP5LMNAALOX5 | |
| 2-Pyrrolidone SCHEMBL28324136 | 0.85 | OR51E2 (0.68) | OR51E2CRBNFKBP5KMT2AKDM4E | |
| Caprolactam SCHEMBL29165574 | 0.84 | CRBN (0.59) | OR51E2CRBNFKBP5ALOX5CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109120-A2 | P53-MEDIATED SKIN PIGMENTATION | DANA-FARBER CANCER INSTITUTE (US) | 2008-09-12 | — | — | WO | disclosed |