Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3465518 | 0.87 | KDM4E (0.33) | SPHK1 | |
| SCHEMBL1858563 | 0.84 | SPHK1 (0.33) | SPHK1 | |
| SCHEMBL4974483 | 0.84 | SPHK1 (0.33) | SPHK1 | |
| SCHEMBL3466182 | 0.83 | SPHK1 (0.35) | SPHK1 | |
| SCHEMBL3466633 | 0.83 | SPHK1 (0.46) | SPHK1 | |
| SCHEMBL3466629 | 0.83 | SPHK1 (0.46) | SPHK1 | |
| SCHEMBL1067660 | 0.80 | SPHK1 (0.31) | SPHK1 | |
| SCHEMBL3614629 | 0.80 | SPHK1 (0.31) | SPHK1 | |
| SCHEMBL1067656 | 0.80 | SPHK1 (0.31) | SPHK1 | |
| SCHEMBL3213291 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |