SCHEMBL4970262

SCHEMBL4970262

CO[Si](C)(CCSC(C)=O)OC

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.40
POLB P06746 1/20 0.39
BLM P54132 1/20 0.39
ATM Q13315 1/20 0.39
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29211227 0.88 CYP2C19 (0.38) CYP2C19POLBBLMATMHDAC3
SCHEMBL28673870 0.83 CYP2C19 (0.40) CYP2C19POLBBLMATMHDAC3
SCHEMBL3656326 0.80 CYP2C19 (0.41) CYP2C19POLBBLMATMHDAC3
SCHEMBL19640265 0.79 CYP2C19 (0.38) CYP2C19POLBBLMATM
SCHEMBL27523582 0.78 CYP2C19 (0.36) CYP2C19POLBBLMATM
SCHEMBL334696 0.77 CYP2C19 (0.33) CYP2C19POLBBLMATMHDAC3
SCHEMBL12345651 0.77 CYP2C19 (0.46) CYP2C19POLBBLMATMHDAC3
SCHEMBL19640251 0.75
SCHEMBL17069681 0.74 CYP2C19 (0.48) CYP2C19POLBBLMATMHDAC3
SCHEMBL12345649 0.73 CYP2C19 (0.43) CYP2C19POLBBLMATMHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113795499-A Process for producing alkoxysilyl group-containing thiocarboxylic ester 迈图高新材料公司 2021-12-14 CN claimed
CN-113795499-A Process for producing alkoxysilyl group-containing thiocarboxylic ester 迈图高新材料公司 2021-12-14 CN disclosed
CN-105452261-B continuous process for preparing thiocarboxylate silane 莫门蒂夫性能材料股份有限公司 2019-12-10 CN disclosed
US-10246581-B2 Rubber compositions containing whey protein BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2019-04-02 US disclosed
US-20170342253-A1 RUBBER COMPOSITIONS CONTAINING WHEY PROTEIN BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2017-11-30 US disclosed
EP-1270581-B1 Blocked mercaptosilane coupling agents for filled rubbers MOMENTIVE PERFORMANCE MAT INC (US) 2014-02-19 EP disclosed
EP-0958298-B2 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS MOMENTIVE PERFORMANCE MAT INC (US) 2008-10-22 EP disclosed
US-20070083011-A1 Blocked mercaptosilane coupling agents for filled rubbers MOMENTIVE PERFORMANCE MATERIALS INC. 2007-04-12 US disclosed
US-7122590-B2 Silicon compounds such as 2-triethoxysilyl-1-ethylthioacetate, used as binders of rubbers such as butadiene-styrene copolymers, containing fillers GENERAL ELECTRIC COMPANY (US) 2006-10-17 US disclosed
US-20060183866-A1 Blocked mercaptosilane coupling agents for filled rubbers MOMENTIVE PERFORMANCE MATERIALS INC. 2006-08-17 US disclosed
US-20030225195-A1 Silicon compounds such as 2-triethoxysilyl-1-ethylthioacetate, used as binders of rubbers such as butadiene-styrene copolymers, containing fillers CROMPTON CORPORATION 2003-12-04 US disclosed
US-6608125-B2 2-triethoxysilyl-1-ethyl thioacetate; tires CROMPTON CORPORATION 2003-08-19 US disclosed
EP-0958298-B1 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS CROMPTON CORP (US) 2003-05-07 EP disclosed
EP-1270581-A2 Blocked mercaptosilane coupling agents for filled rubbers CROMPTON CORPORATION (US) 2003-01-02 EP disclosed
US-20020099118-A1 For use in tires, shoe soles WITCO CORPORATION, A CORPORATION OF THE STATE OF DELAWARE 2002-07-25 US disclosed
US-6414061-B1 CURABLE MIXTURE CROMPTON CORPORATION 2002-07-02 US disclosed
US-20020055568-A1 3-(acylmercapto)propyltrialkoxy- or trihydroxysilane WITCO CORPORATION 2002-05-09 US disclosed
US-20020055564-A1 Sulfur silane coupling agents which are latent WITCO CORPORATION 2002-05-09 US disclosed
EP-0958298-A1 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS WITCO CORPORATION (US) 1999-11-24 EP disclosed
WO-1999009036-A1 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS OSI SPECIALTIES, INC. (US) 1999-02-25 WO disclosed